The city of Glasgow is characterized by the largest age-related health disparity in the developed world. The concept of frailty, its effects on health outcomes and its social patterning, was first developed in Glasgow by Bernard Isaacs and described in his seminal text 'Survival of the unfittest'.
To understand and target interventions to mitigate the effects of an advancing ageing process and the resultant ‘diseasome of ageing’.
To undertake a cross disciplinary life course approach to understanding the ageing process, mitigating its detrimental effects and developing suitable( pharmacological and non-pharmacological) interventions to improve healthspan .